Stomach pain without eating is called fasting stomach pain and is most commonly associated with duodenal lesions, such as duodenal inflammation, erosion, ulcers, polyps, and even malignant tumors. In addition to stomach pain, there may be other symptoms such as indigestion, acid reflux, nausea, dry mouth, bitter mouth, and bad taste in the mouth, etc. To confirm the diagnosis, it is best to have a gastroscopy. Its treatment mainly includes 2 aspects: 1. Inhibition of gastric acid secretion, such as the commonly used omeprazole, pantoprazole, rabeprazole, etc.. In addition, it is also necessary to promote mucosal repair, such as Schilling, Metzolim, rehabilitation new liquid, etc. 2, if the pain is more severe can be temporarily taken gastric mucosal protective agent, such as Daxil, etc. If the duodenal lesion is accompanied by H. pylori infection, anti-H. pylori treatment is also required.