Except for a few patients who are insulin-dependent and must be treated with insulin injections, most diabetic patients only need to take some oral hypoglycemic drugs to keep their disease under control on the basis of diet control. Diabetes is a lifelong disease that requires a lifetime of treatment. In order to maintain good results, family medication must pay attention to the following 9 points: 1, long-term use of a preparation, can gradually see ineffective, then must be promptly replaced with another preparation. 2, pay attention to the combination of drugs, in order to use reasonable doses or caution, ban certain drugs. For example, the simultaneous use of sulfonylureas and dipyridamides may enhance the hypoglycemic effect. The hypoglycemic effect is enhanced when sulfonylurea is used together with the following drugs: salicylic acid and its salts, aminopyrine, pautazone, sulfonamides, guanidine, rifampicin, colistin, insulin, tetracycline, chloramphenicol, anti-inflammatory pain, etc. The hypoglycemic effect is weakened when used together with the following drugs: isoptin, nifedipine, diuretics, corticosteroids, thyroid hormone, estrogen, rifampin, barbiturate, chlorpromazine, oral contraceptives. Chlorpromazine, oral contraceptives, etc. 3. Oral hypoglycemic drugs are suitable for non-insulin-dependent diabetes mellitus when the blood sugar level is still high after simple diet control. 4. The medication should be taken regularly and quantitatively as prescribed by the doctor, and the medication record should be made. The record should include the name of the medicine, the dose and its increase or decrease, the method of taking the medicine, the reaction after taking the medicine, the results of blood sugar and urine sugar examination, and the diet. 5, all kinds of preparations, it is appropriate to start with a smaller dose, every morning to take one, and then gradually increase the dose according to the condition and efficacy is more stable. 6.If you have gastrointestinal discomfort, skin allergy, leukopenia, impaired liver function or hypoglycemic reaction, you should seek medical attention in time. 7. Pay attention to the patient’s liver and kidney function. Oral hypoglycemic drugs (except sugar nephrite) are metabolized in the liver and excreted by the kidneys, so they should not be used in diabetic patients with liver and kidney insufficiency. 8, the efficacy of herbal preparations is not certain, it is appropriate to use as adjuvant therapy, or for the treatment of light, stable patients. 9, oral hypoglycemic drugs in sufficient doses for a period of time, if blood sugar is always very high, the efficacy is not obvious, you can switch to insulin therapy.