Most enlarged tonsils are enlarged due to acute inflammation of the tonsils. Acute inflammation is usually caused by acute upper respiratory tract infection, the pathogenic bacteria are mostly hemolytic streptococci, which are more sensitive to penicillin anti-inflammatory drugs, you can take cefixime, cefuroxime, cefradine, cefaclor. If cephalosporin allergy, you can take oral azithromycin, roxithromycin and so on. It can also be combined with proprietary Chinese medicines, such as Lianhua Qingdian Capsule, Blue Scutellaria Oral Liquid, Shuanghuanglian Oral Liquid, and Slowly Lianshu Lime Granules. However, if the effect of oral anti-inflammatory drugs is poor, infusion therapy is needed, which can be infused with cefazolin sodium, cefotaxime sodium, ceftriaxone sodium, cefradine, cefoperazone, or metronidazole and levofloxacin. However, in the case of more severe symptoms, antibiotics need to be changed, or antibiotic dosing can be elevated, or meropenem and cefsulbactam sodium can be used for a course of about a week.