How long a patient with hypofractionated squamous carcinoma can live depends on the patient’s recovery after treatment and whether metastasis occurs. Hypofractionated squamous carcinoma indicates that the malignancy of cancer is relatively high, and cancer cells are more likely to metastasize at the early stage of tumor, local infiltration and invasion, etc. Its overall prognosis is worse than that of medium and high fractionated squamous carcinoma. However, the estimation of specific survival depends on the stage of the tumor, that is, whether the tumor is detected in time and whether it is an early stage tumor. If the hypofractionated squamous carcinoma is detected in time, before any metastasis occurs, and if it receives standardized anti-tumor treatment in time, it can still achieve more satisfactory results and even cure long-term survival, but for advanced hypofractionated squamous carcinoma, the expected survival time is about six months to one year, and it is expected to be worse than that of medium and high fractionated squamous carcinoma. poorer than that of middle and high grade squamous carcinoma. In conclusion, the survival of patients with hypofractionated squamous carcinoma cannot be generalized, but early diagnosis and treatment can prolong their survival.