Calf bone fracture generally refers to fibula tibia fracture, patients need to be treated through medication, surgical treatment, general measures for care. 1. Medication: Usually when patients have serious pain symptoms, they should follow the doctor’s instructions to use Celecoxib, Tramadol and other painkillers, and also need to use warfarin sodium, rivaroxaban and other drugs to prevent venous thrombosis. 2. Surgical treatment: patients need to choose internal fixation of steel plate, intramedullary nail, external fixation bracket, bone grafting, bone traction and so on according to their own situation in time and after assessment by doctors. 3. General measures: After local immobilization, patients should carry out ankle dorsiflexion activities and quadriceps contraction exercises under the guidance of doctors, and also need to carry out leg lifting and knee flexion activities appropriately. Patients need to avoid direct and indirect violence, and pay more attention to rest, appropriate elevation of the affected limb, can relieve swelling. At the same time, patients also need to ensure a balanced diet and quit smoking in time, so as not to affect the healing of the fracture. It is recommended that patients with tibiofibular fractures take targeted treatment under the guidance of a doctor and pay more attention to their own care.