NSE is the abbreviation of neuron-specific enolase, which mainly exists in nerve cells and neuroendocrine cells. High NSE is the result of tumor marker examination and is often used for screening of small cell lung cancer, but cranial injury, brain infection, etc. may also lead to high NSE. High NSE alone is generally not diagnostic of the disease and requires further examination through brain MRI, chest CT, pathological biopsy, etc. to clarify the cause. 1. Mildly elevated: generally inflammation of neural tissue, such as encephalitis, cranio-cerebral injury, etc. Encephalitis may have symptoms such as headache, vomiting and fever, which can be treated by hydrocortisone and dexamethasone as prescribed by the doctor; cranio-cerebral injury usually has a history of trauma, and serious cases need surgery to reduce intracranial pressure; 2, severe elevation: if the elevation is more than 5-10 times, small cell lung cancer is suspected, and the patient may also have symptoms such as dry cough, hemoptysis and difficulty in breathing. , to find the primary lesion. Sometimes small cell lung cancer will appear after 6 months or 1 year of high NSE, so patients should be reviewed regularly, once in 3-6 months or so. In addition, neuroblastoma, medullary thyroid carcinoma, pheochromocytoma, etc. may also have high NSE and need to be identified by ultrasound and MRI, etc. Do not be too anxious when NSE is high, but seek medical advice and follow the medical treatment. Patients should quit smoking and drinking in their daily life, and eat less spicy and stimulating food, such as hot pot and barbecue. Pickled foods should also be eaten sparingly, such as bacon, pickles, etc. You can usually eat more fresh vegetables and fruits, such as celery, cabbage, apples and pears.