Clinically, depending on the severity of the localized pus in the patient’s big toe, different treatment methods are often available: 1. If the patient’s local infection of the big toe is relatively mild, and there is no more accumulation of fluid and pus, the patient can use Bactrim or ichthyolite ointment or vital iodine gauze for continuous wet compresses, and ask the patient to take oral amoxicillin, levofloxacin and other antibacterial drugs, so that the less localized pus is absorbed on its own in 3-5 days to achieve better results. 2.If the local infection of the big toe is more serious, with more local pus accumulation, and accompanied by toenail and nail bed damage, it is recommended that the patient under local anesthesia to perform local abscess incision and drainage, if necessary, the toenail needs to be removed, using hydrogen peroxide vital nasal and other drugs to thoroughly rinse, Vaseline gauze stuffing drainage, while intravenous infusion of antibacterial drugs to strengthen anti-infection treatment. The local inflammation can be controlled more quickly.