Burning sensation in the stomach is generally considered to be caused by excessive secretion of gastric acid due to physiological or pathological factors, which can be treated by medication, endoscopic treatment, surgical treatment and so on. 1. Drug treatment: such as omeprazole enteric-coated tablets, pantoprazole sodium enteric-coated capsules, etc., through the inhibition of gastric acid secretion, so as to reduce the stimulation of gastric acid on the mucous membrane. 2. Endoscopic treatment: when the burning sensation in the stomach is caused by peptic ulcer, endoscopic treatment can be carried out, such as spraying protein gel on the surface of the ulcer, injecting epinephrine at the bleeding site, bleeding point clamping and thermal coagulation, etc., and sometimes more than two kinds of combined use; when peptic ulcer combined with pyloric deformity or stenosis, endoscopic treatment can be chosen, such as endoscopic variable balloon dilatation. 3. Surgical treatment: laparoscopic fundoplication, which can stop the flow of gastroduodenal contents into the esophagus, can be considered for patients with gastroesophageal reflux who have persistent heartburn and consequent chronic cough, pharyngitis, and limited drug treatment. Patients with heartburn should usually pay attention to less intake of stimulating foods, avoid increasing obesity and other factors that increase abdominal pressure, and should not lie flat too soon after meals.