Viral infections, bacterial infections, and specific pathogen infections are the main considerations for children with a bad cough at night. Coughs from viral infections can be treated with antiviral medications. Cough caused by bacterial infections can be treated with antibiotics such as cefixime. In addition, we need to be alert to special pathogen infections, such as mycoplasma infection, whooping cough infection. 1. Viral infection cough: If there is a significant cough at night within a short period of time, it is usually related to viral infection. Viral colds are self-healing and are estimated to resolve within 5 to 14 days. If it is caused by influenza virus, antiviral drugs such as oseltamivir can be used as prescribed by the doctor. 2. Bacterial infection cough: bacterial infection can also lead to the child’s cough at night is more obvious, you can choose antibiotic treatment under the guidance of the doctor, such as amoxicillin clavulanate potassium, cefixime and other antibiotics anti-infection treatment. If necessary, sputum culture can be perfected, and according to the results of sputum culture timely adjustment of antibiotic use. There are many different reasons for children to have a cough at night, which may also be caused by gastroesophageal reflux, cough variant asthma and other diseases, in any case, all of which should be examined in a regular hospital, and then take targeted treatment.