In the human skeleton, the skull is the hardest, it is the hard shell to protect the human brain. However, even if the skull is hard, it can not withstand the impact of some external gravity, and inevitably such problems as cranial defects. Once the human skull is damaged, the brain tissue lacks proper protection and the situation is quite dangerous. After skull defect, the intracranial pressure is extremely unstable, which will directly affect the circulation of cerebrospinal fluid and blood inside the skull, making it difficult for the brain tissues to function normally, and it is also very unattractive from the appearance. Therefore, it is necessary to perform skull repair surgery in time, both from the health and aesthetic point of view. The choice of materials is a crucial part of skull repair surgery, and good materials can achieve more ideal repair results. Nowadays, titanium mesh material is widely used in some local hospitals, which has some progress compared with traditional bone cement and plexiglass, but some defects cannot be avoided. The common ones are post-operative infection and rejection, and even scalp tissue damage, and the heat insulation of titanium mesh material is not very good, so patients will become sensitive to hot and cold environment after surgery. Can MRI be done with titanium mesh for skull repair? This is also a critical point, because titanium mesh is a metal material, it will interfere with the transmission of radiation and affect the postoperative CT MRI and other examinations, interfering with the final diagnosis. Therefore, to perform better skull repair surgery, a more advanced high-tech material is needed, and polyetheretherketone-PEEK material is a good choice. We use PEEK material to perform cranial repair surgery, and we continue to innovate and upgrade our surgical techniques and introduce the concept of cosmetic surgery to achieve good repair results, achieving structural integrity, functional perfection, and aesthetic unity, with a wealth of clinical cases and affirmative postoperative results.