Spots on hands, commonly found in age spots, freckles, age-related white spots, etc., need to be eliminated by different methods according to the nature of different spots, so there is no fastest one. 1. Age spots: it refers to brown spots with the size of rice grains to nail cap on the exposed parts of face and back of hand, with clear boundary, seborrheic scabs on part of the surface and hyperkeratosis, which belongs to senile skin changes and generally does not need special treatment. Patients who need treatment can use 5-fluorouracil ointment, vitamin E and other medicines externally, and can also use physical methods such as laser, freezing and electrocautery to play the role of lightening color spots. 2. Freckles: manifested as light brown or dark brown spots, commonly found on the face and also on the hands. Generally there is no need for special treatment, and it can be covered by sun protection and cosmetics. It can also be spot-coated with trichloroacetic acid solution or phenol to promote the stripping of spots, but it is easy to lead to scarring and pigmentation disorders, so it is seldom used; or the use of intense pulsed light or liquid nitrogen freezing and other methods, which can also play a certain role in lightening. 3. Age-related white spots: belonging to the age-related skin degenerative phenomenon, the cause of which is not yet clear, and is considered to be a physiological phenomenon of skin aging. It can lead to the appearance of round or oval white spots with the size of a needle tip to a green bean on the local skin of patients. Generally there is no need for treatment, as long as you do a good job of avoiding light, sunscreen can be. There are many reasons for the appearance of abnormal spots on the hands, and it is recommended that patients go to the hospital in time to clarify the cause of the disease and follow the doctor’s instructions to standardize the treatment.