Blistering eczema on the hands can be helped by topical medications, oral medications, paying attention to nursing, and avoiding irritating factors. 1. Topical drugs: blistering eczema on the hands can use hydrocortisone butyrate ointment, dexamethasone ointment and other glucocorticoid ointment topical application to help anti-inflammatory, anti-allergic, so as to effectively alleviate the symptoms. For patients with more localized exudation, they can use boric acid solution, esamethasone solution and other cold wet compresses, and then use glucocorticoid creams such as dexamethasone for treatment. 2. Oral medication: For patients with more pronounced itching symptoms of blistering eczema on the hands, you can take oral cetirizine, loratadine tablets and other antihistamines under the guidance of a physician to help relieve the itching symptoms. 3. Attention to care: patients should pay more attention to the care of localized skin lesions. The blisters are generally small and can be absorbed on their own, so there is no need for excessive treatment. If the blisters are large, you can use a sterile syringe to extract the blister fluid, sterilize it and then apply medication, and avoid scratching and squeezing to avoid infection. 4. Avoid irritating factors: In the process of treatment, in order to achieve better therapeutic effect, patients should pay attention to avoid contact with irritating substances, such as hand sanitizer, disinfectant water, etc.; dietary attention should be paid to not eat irritating foods, such as seafood, durian, mango, beef, etc., so as not to aggravate the condition. If the symptoms of blistering eczema on the hands are not relieved, or accompanied by other symptoms, you should go to the hospital in a timely manner, to identify the cause and then give targeted treatment.