Esophageal cancer, i.e. esophageal cancer, can be treated with medication and endoscopic treatment when it is detected in an 85-year-old man. If the patient’s physical condition permits, he/she can undergo surgical treatment. 1. Drug therapy: patients with esophageal cancer can be treated with molecular targeting drugs such as gefitinib tablets and erlotinib hydrochloride tablets as prescribed by doctors. Chemotherapy drugs such as 5-fluorouracil injection, cisplatin injection, paclitaxel injection, irinotecan injection and so on can also be applied according to medical advice. 2. Endoscopic treatment: patients with early stage of esophageal cancer can adopt endoscopic treatment, and the main treatment modes are endoscopic mucosal resection, endoscopic submucosal dissection, endoscopic non-excision treatment and so on. 3. Surgical treatment:85-year-old patients with esophageal cancer can take surgical treatment if they are in good physical condition and have no contraindication to surgery, including conventional open thoracic surgery, thoracoscopic surgery and other surgical methods. After 85-year-old people find out esophageal cancer, they should seek medical treatment in time and take specific treatment under doctor’s guidance, and patients should not take medication without authorization.