The baby has been coughing and taking medicine has no effect, may not be according to the doctor’s orders or cough cause is not clear, no targeted medication, etc., need to comply with the doctor’s orders to take medication, or a clear cause of targeted treatment, etc.. Cough is a reflex defense action, through the cough can clear respiratory secretions and airway foreign body, treatment can be improved, but the baby has been coughing and taking medication has no effect, there may be the following reasons: 1. not according to the doctor’s orders: baby compliance is poor, sometimes not enough medicine enough, or enough treatment. It is recommended to try to follow the doctor’s instructions, and the drug should be taken according to the course of treatment, try to achieve the full amount of full course of treatment. 2. not the cause of treatment: the baby cough for many reasons, if it is allergy caused by coughing, the application of anti-allergy drugs for treatment, if it is mycoplasma infection caused by coughing, need to use azithromycin and so on for treatment. If the medicine is not right, single use of antibiotics such as cefaclor or cough and phlegm treatment, may cause long-term cough. The reason for the cough is clear and targeted. The baby has been coughing and taking medicine is not effective may also have other reasons, it is recommended to go to the hospital in time to improve the examination to clarify the cause of the disease, to give targeted treatment or treatment. The medication is in accordance with the doctor’s instructions.