The ratio of diuretic combination needs to be operated according to different drugs and conditions, such as dopamine and tachycardia often start with a small dose ratio and gradually increase. Diuretic combinations are mainly used to treat symptoms of oliguria due to chronic renal failure, but can also be used to treat persistent heart failure. Diuretic combinations contain a variety of drugs, usually dopamine as well as tachycardia used in combination, the specific method of preparation of the two drugs, depending on the condition. Clinical use of these two drugs, as far as possible to small doses, small doses of dopamine has the effect of dilating the renal arteries, can increase the perfusion of the kidneys. On the basis of increasing renal perfusion, giving diuretic medication can significantly improve the filtration function of the kidneys and increase the patient’s urine output. Therefore, the application of diuretic combinations is conducive to the discharge of harmful substances in the body, the discharge of excess water in the body, the reduction of the load on the heart, and the promotion of the recovery of renal function. However, cardiac monitoring should be carried out on patients, and the medication should be adjusted according to the patient’s blood pressure, heart rate, urine output and edema. Patients who need to apply diuretic combination, it is recommended to go to the regular hospital in time, under the guidance of the doctor to use, avoid self-medication.