In non-obstructive hypertrophic cardiomyopathy, some of the myocardium will keep thickening, while some of the condition is stable and the myocardium will not keep thickening. Non-obstructive hypertrophic cardiomyopathy patients, because the left ventricular outflow tract has not yet occurred obstruction, so the condition of the early stage of most patients with clinical symptoms are not obvious, most do not need to do special treatment, it is recommended that close observation, regular follow-up cardiac function, echocardiography. Hypertrophic cardiomyopathy is a chronic heart disease with an unclear etiology, and may run in families. In many patients, the thickening of the myocardium is very slow, and the myocardium may not thicken significantly for many years. In a few patients, the disease progresses more rapidly, with progressive myocardial hypertrophy, eventually leading to obstructive hypertrophic cardiomyopathy and even heart failure. When the symptoms of heart failure need to be actively drug treatment, the use of drugs including beta-blockers, such as propranolol, metoprolol, can reduce the outflow tract obstruction, reduce myocardial oxygen consumption. β-blocker treatment is ineffective patients, can be applied to calcium channel blockers, such as verapamil, can reduce the left ventricular outflow tract pressure difference, improve diastolic filling and local myocardial blood flow, follow the doctor’s instructions for medication.