At high doses it can induce histamine release. Indicated for muscle relaxation for endotracheal intubation and muscle relaxation required for thoracic and abdominal surgery Non-depolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation and to allow skeletal muscle relaxation during surgical procedures or controlled ventilation. Assists in artificial ventilation for patients in the intensive care unit. It is used for various surgical procedures requiring muscle relaxation or controlled breathing situations. In summary, atracurium has a variety of effects and should be used under the close supervision of an anesthesiologist and should be equipped for tracheal intubation and artificial ventilation. Patients with severe cardiovascular disease should be injected slowly and in small doses, and the rules of administration must be observed.