Pentavalent rotavirus and polio should be pentavalent rotavirus vaccine and polio vaccine, generally not recommended at the same time, it is recommended to separate vaccination, more than 2 weeks apart. Pentavalent rotavirus vaccine and polio vaccine belong to two different viral vaccines, due to the virus, there may be interference between the phenomenon, which in turn affects the preventive effect of the vaccine after the vaccine, it is generally not recommended to receive these two vaccines at the same time, it is recommended that at least 2 weeks apart, so that the two vaccines to produce antibodies to each other does not affect the time. In addition, vaccination may produce some fever, allergies and other side effects, if the two vaccines are given at the same time, it may lead to an increase in the adverse reaction to the vaccine. Parents are not recommended to give their children two vaccinations at the same time to avoid affecting their children’s health. When discomfort occurs after vaccination, please consult the hospital in time to avoid adverse consequences.