Acute cryptogenic tonsillitis, infectious mononucleosis, Fanshawang pharyngitis and other diseases can cause inflammation of the tonsils red, swollen and pus, according to the different diseases need to be targeted treatment, including general treatment, medication and other methods to control the disease and improve symptoms. 1. Acute cryptogenic tonsillitis: patients with this disease have severe sore throat, preferred penicillin for treatment, if the condition does not improve after 2-3 days of treatment, and high fever does not subside, need to consider switching to other antibiotics. Local use of compound borax solution, compound chlorhexidine gargle solution gargle. If it causes complications such as peripharyngeal abscess, consider surgical treatment after the inflammation subsides. 2. Infectious mononucleosis pharyngitis: It is a pharyngitis caused by EBV infection, which can present with sore throat, congested and enlarged tonsils, white exudate visible in the traps, and occasionally pseudomembrane can be formed, which looks as if it is suppurating. Most can heal on their own, and there is no specific medication available. Bed rest is required in the acute stage. 3. Fanshuang pharyngitis: this disease manifests as unilateral sore throat, the lesion is covered with thick and dirty pseudomembrane, yellow or grayish-white, which is the necrotic material of the ulcer, and it is easy to mistake it for suppuration. Penicillin can be used first according to experience, while taking secretions for culture and drug sensitivity test, and adjust antibiotics when the results come out, and patients can take non-steroidal anti-inflammatory drugs, such as ibuprofen, if they have high fever. At the same time, pay attention to isolation, rest, and gargle diligently. It is recommended that the patient actively consult a doctor for a clear diagnosis, and follow the doctor’s instructions to standardize the use of drugs and treatment.