When the patient presents with headache and generalized soreness, weakness and chills, it is mostly considered that the patient is suffering from upper respiratory tract infection and low-grade fever. Infectious headache will occur due to the effect of viral and bacterial toxins; low fever will cause generalized soreness and weakness. When the body temperature is in the ascending phase, the body will also be in the symptom of chills. In addition, it is also considered that the patient may have a central nervous system infection, such as viral encephalitis or bacterial encephalitis. If the patient has neurological symptoms and signs, it is recommended that the patient should go to the neurology department, and if necessary, lumbar puncture and cerebrospinal fluid examination can be carried out to exclude the central nervous system infection. It is recommended that the patient drink plenty of warm water and undergo appropriate blood and urine tests and head CT.