Hashimoto’s thyroid disease with thyroid nodules can be operated on, but surgery is usually not needed for benign nodules without symptoms. If symptoms develop, then consider surgical removal. Hashimoto’s thyroid disease is a chronic autoimmune inflammation of the thyroid gland, and thyroid nodules are caused by abnormal localized proliferation of thyroid cells. For patients with Hashimoto’s Thyroid Disease with thyroid nodules, if the nodules are benign and asymptomatic, surgery is not necessary and regular checkups are sufficient. However, if the nodules are large enough to cause symptoms such as difficulty in breathing and swallowing, surgery is required. Surgical options include total thyroidectomy, lobectomy, microwave ablation, and lumpectomy. Patients should choose the appropriate surgical procedure according to their individual situation. Patients with Hashimoto’s Thyroid Disease with thyroid nodules are advised to visit their local hospitals for a detailed consultation to determine if they want surgery.