Elderly people are prone to acute myeloid leukemia. Elderly people are in a process of decreasing body functions, and their resistance to various internal and external factors is reduced, so the possibility of mutation is higher than that of middle-aged and young people. The incidence of AML is increasing year by year, the average age of onset is 60~75 years old, but the main age group with high incidence is 80~85 years old. Elderly patients with AML have a poorer prognosis, and the complete remission rate decreases with age. Therapeutic drugs include Vinaclat, Azacitidine, and Cytarabine. Elderly people must have healthy living habits in daily life, pay attention to healthy diet, physical and mental pleasure, reasonable exercise and other preventive measures, will reduce the possibility of AML to a certain extent. If the elderly suffer from AML, please consult a doctor in time to receive reasonable and standardized diagnosis and treatment.