The poor effect of Azithromycin after three days of glans inflammation may be that the medication is not appropriate, at this time, we need to clarify the cause, and give general treatment, medication (ketoconazole ointment, etc.), physical therapy and other ways of treatment for the cause of the disease. There are many causes of glans, such as bacterial infection, mycoplasma infection, viral infection, fungal infection and external stimulation, etc. Azithromycin can be used to treat glans caused by bacterial infection and mycoplasma infection, and is ineffective for glans caused by other factors. At this time, it is necessary to clarify the cause of the disease, and then give the appropriate treatment for the cause, such as general treatment, drug treatment (ketoconazole ointment, etc.), physical therapy and so on. 1. General treatment: the general need to pay attention to genital hygiene, can be used daily warm water for cleaning, especially the circumcision patients, pay attention to the circumcision and the glans at the cleaning, can not use soap and water cleaning. 2. medication: the cause of glans is more, so the use of drugs are also different, such as by herpes simplex virus infection, need to give the relevant antiviral drug therapy, such as acyclovir, update lovir, etc.; Candida albicans infection, you can give antifungal drug therapy, such as ketoconazole ointment. 3. Physiotherapy: If necessary, infrared irradiation treatment can be given to the glans and other physiotherapy, which can help the recovery of glansitis. It is recommended that the patient go to the hospital, improve the auxiliary examination, clarify the cause of the disease, and give the appropriate treatment for the cause of the disease.