Causes of high aspartate aminotransferase

Patients with high aspartate aminotransferase are mostly considered to have liver function impairment. If the patient’s transaminases are elevated between 40 and 80 U/L, functional liver damage is considered, which means that the patient has been drinking alcohol, taking medication, being tired, staying up late, or eating fatty food in the week before the blood test, all of which can cause transient damage to liver function. In this case, patients need to actively change their daily habits and can take dicyclomine tablets and bupropion drops in appropriate amounts to actively lower transaminases. If the aminotransferases are elevated above 80 U/L, the patient is likely to have underlying liver disease, most commonly due to viral hepatitis. In this case, further blood tests are needed to see if the virus is replicating. If the virus is replicating, combined with elevated transaminases, we should actively consider antiviral treatment along with liver protection therapy.