The metabolically active and irregular shape of ribs is a description of the condition of ribs in nuclear medicine examination, and the causes of the corresponding condition mainly include rib fractures, rib tumors and infectious lesions. 1. Rib fracture: after trauma, rib fracture, local hematoma mechanization, granulation tissue formation, there will be rich local blood flow, active metabolism and irregular bone shape. 2. Rib tumor: the most common one is metastatic tumor of the rib, the local tissue cell proliferation is active, causing the destruction of the surrounding bone, which will cause metabolic activity and irregular bone shape. 3. Infectious lesions: local inflammatory reaction can also lead to capillary proliferation, local bone destruction, resulting in metabolically active and irregular bone morphology. If the ribs are metabolically active and irregular in shape, it is necessary to consult a doctor in time for observation, to confirm the specific condition, and to carry out standardized treatment under the guidance of the clinician to avoid the delay of the condition.