Pentavalent vaccine should not be administered in cases of allergy to the components of Pentavalent vaccine, fever, acute illness, acute exacerbation of chronic diseases, serious adverse reactions to previous vaccinations containing the same components, or immunologic abnormalities. 1. Allergy to the components of the DPT vaccine: No matter which component of the DPT vaccine you are allergic to, you are prohibited from receiving the DPT vaccine. 2. Fever: People who are in a state of fever need to postpone vaccination with DPT. 3. Acute illness or acute exacerbation of chronic disease: People who are suffering from an acute illness or an acute exacerbation of a chronic disease should not be vaccinated with the DPT vaccine, and should wait until their condition is stabilized or they have recovered before they can be considered for vaccination. 4. Serious adverse reactions to previous vaccinations containing the same components of the vaccine: If you have previously received some vaccines with the same components as the DPT, but there are fatal serious adverse reactions, you cannot receive the DPT. 5. Immune abnormalities: individuals who are using immunosuppressants for treatment or suffering from immunodeficiency diseases should not be vaccinated with the DPT, so as not to reduce the body’s immune response to the vaccine, which will affect the effectiveness of the vaccine injection. Although the Pentavalent vaccine can prevent five diseases at the same time, but not everyone is suitable for the vaccine, individuals need to strictly contraindications, so as to avoid their own wrong vaccination behavior, bringing unnecessary damage to the individual. If you have any abnormal symptoms after receiving the Pentavalent vaccine, you can consult a medical professional.