There are certain side effects of medicated film to remove spots, the medicated film to remove spots contains chemicals with acid composition, after removing spots, there is a possibility of rotting face and returning to blackness, which is mainly caused by acid burning and stimulation of the skin. Then there can be hormone-dependent dermatitis. Long-term application of medicated film to remove spots can lead to dry skin and damage to the skin barrier, which may result in localized capillary dilation and the formation of sensitive skin, followed by the formation of hormone-dependent dermatitis. In addition, the film may also contain alcohol components, after the application of film to remove spots, the skin may appear erythema, papules, blisters, as well as accompanied by itching, and even pus liquid exudation and other clinical skin manifestations of contact dermatitis. Therefore, in order to remove spots with medicated film, it is necessary to go to qualified medical institutions and choose regular medicated film to remove spots under the guidance of dermatologists.