If severe pregnancy sickness occurs, the first thing that should be done is to run tests for urinalysis, inorganic ions, liver and kidney function, and obstetric ultrasound. If there is no abnormality in the obstetric ultrasound and the embryo is developing well, but there are ketone bodies in the urinalysis and inorganic ion imbalance, this case should be hospitalized and fluid rehydration therapy should be given. At the same time, severe vomiting should be prohibited from eating and drinking, the amount of rehydration fluids should be greater than 3,000 ml per day, and the fluids should be supplemented with vitamin B6, vitamin B1, and vitamin C for multi-nutrient therapy. If necessary, amino acids and fat milk should also be given for nutritional treatment, and attention should be paid to potassium supplementation. If there are electrolyte disorders, the appropriate ions should be supplemented according to the laboratory results. At the same time, attention should be paid to review the urine, and if necessary, sodium bicarbonate should also be given to correct acid therapy.