The symmetrical whitening of the hands without blood is considered to be related to cold stimulation, anemia and other factors, treatment should be based on the cause of the general treatment, drug therapy and other ways of treatment. 1. Cold stimulation: if the patient uses cold water to wash hands or the environment temperature is relatively low when the symmetrical whitening of the hands without blood, this is considered to be a physiological factor, thought to be the cold caused by local vasoconstriction caused by hot compresses, wash hands with lukewarm water and other ways to improve. 2. Anemia: (1) If the patient’s recent intake of nutrients is insufficient, combined with chronic wasting disease: due to the lack of raw materials for hemoglobin synthesis, so the patient will mostly be combined with iron-deficiency anemia, at this time, can follow the doctor’s instructions to supplement iron, if necessary, need blood transfusion. (2) For patients with hematologic disorders, treatment with iron, blood transfusion, glucocorticosteroids such as prednisone, immunosuppressants such as methotrexate, or bone marrow transplantation should be prescribed by the doctor. For patients with symmetrical whitening of the hands without blood color, it is recommended to go to a regular hospital to improve the blood routine and other related examinations, to clarify the cause of the disease under the guidance of the doctor to actively treat.