Cough with thick yellow sputum is mostly indicative of the presence of inflammation, which usually does not heal on its own. Without timely medication, the condition will progress further and uncomfortable symptoms such as chest tightness, breath-holding and fever may appear. Therefore, this situation needs to be examined by a doctor in a timely manner and treated with medication as prescribed by the doctor after a clear diagnosis. If it is coughing yellow sputum caused by pharyngitis, oral antibiotics such as amoxicillin or amoxicillin clavulanic acid potassium, cephalexin can be taken for treatment. If coughing yellow sputum is caused by bronchitis or pneumonia, intravenous drip antibiotics are often needed for treatment. Depending on the possible bacteria and severity of the infection, antibiotics such as penicillins, cephalosporins, macrolides and quinolones can be used alone or in combination with anti-inflammatory treatment. Drugs to improve the symptoms of cough and sputum are also given. Cough with thick yellow phlegm can be treated with foods that regulate the spleen and stomach and tonify the lungs, such as pears and radish water. The diet should be light, with less salt and sugar, and do not eat spicy and stimulating foods. Avoid dry indoor air, you can put a humidifier in the room. Avoid smoking and drinking alcohol to avoid irritating the airways and aggravating cough symptoms.