Periodontitis can be treated with medications such as ibuprofen, acetaminophen, metronidazole, and tinidazole for pain relief and anti-inflammation under the direction of a doctor. Periodontitis is mainly an infectious disease caused by plaque, trauma, and other factors, and patients may experience red, swollen, bleeding, and pus-filled gums, as well as tooth pain. Patients can use anti-inflammatory drug medications such as ibuprofen and acetaminophen to relieve pain, as well as drugs such as metronidazole and tinidazole to reduce inflammation and fight infection. However, these medications are generally used as an adjunctive treatment, and patients with periodontitis must thoroughly eliminate plaque, tartar, and other pathogenic irritants in order to bring periodontitis under better control. Patients can be treated with ultrasonic scaling, periodontal scaling, periodontal surgery and so on. It is recommended that patients follow the doctor’s instructions to regulate the treatment, after the use of drugs, different drugs will have different adverse reactions, when there is discomfort, consult the doctor in time.