Inflammatory factors, also called inflammatory mediators, the vascular and leukocyte responses to inflammation, are mediated through the action of a series of chemical factors. These chemical factors that participate and mediate the inflammatory response are called inflammatory mediators. The main of inflammatory factors directly damage the vascular endothelium, leading to increased vascular permeability. Inflammatory factors can lead to inflammatory responses such as fever, pain, vasodilation, increased permeability, and leukocyte exudation. In severe cases, it can cause acute multiple organ failure or death.