Tadalafil and Dapoxetine can be taken at the same time, when men have erectile dysfunction and premature ejaculation, they can take both Tadalafil and Dapoxetine under the guidance of the doctor. 1. Tadalafil: it is a drug for the treatment of erectile dysfunction in men, and may have adverse reactions such as flushing, nausea and vomiting; sildenafil is forbidden to be used in combination with nitrate drugs, and this drug is forbidden for women, those who are allergic to the product, children, and those who are not suitable for sex in recent cardiovascular status. 2. Dapoxetine: generally used in the treatment of male premature ejaculation, reduce the sensitivity of the sperm-control center, reduce the sensitivity of the penile coronal sulcus, so as to improve the phenomenon of premature ejaculation, may be diarrhea, dizziness, headache and other symptoms; allergic to any component of the product, are taking any form of nitrate drugs, guanylate cyclase stimulants, women, children and other groups of people prohibited tadalafil. The combination of tadalafil and dapoxetine can help relieve erectile dysfunction and premature ejaculation in men. However, the medication should be taken in doses under the guidance of a doctor to avoid unnecessary damage to the body from unauthorized use.