When it comes to chemotherapy, most patients are full of fear, especially about the side effects of chemotherapy. Most patients with malignant tumors need chemotherapy to kill the malignant tumor cells in their body, but most of the chemotherapeutic drugs do not have targeting, killing the tumor cells at the same time inevitably kill part of the normal cells, which causes a series of adverse reactions such as bone marrow suppression, nausea and vomiting, liver and kidney function damage and hair loss, etc., of which gastrointestinal tract reactions are the most common. Therefore, during chemotherapy, most patients have poor appetite and weak body, how to regulate the diet so that the patient can recover as soon as possible, so as not to delay the next step of the treatment becomes particularly important. In Chinese medicine, patients are required to avoid food due to its possible incompatibility with each other, while Western medicine advocates comprehensive and balanced nutrition without any special taboos. Compared with normal people, chemotherapy patients should increase their daily protein and calories by at least 20%, and ensure that their daily carbohydrates are about 600-800g and proteins are about 70-100g, and the food should be easily digested and absorbed. Daily life diet should pay attention to the nutritional rational mix, food diversification, eat more high protein, high vitamin, low fat and fresh fruits and vegetables, but during the chemotherapy period should limit the 5-hydroxytryptamine-rich fruits and vegetables, such as bananas, walnuts, eggplants, etc., in order to avoid the activation of the vomiting center in the brain, causing or aggravating nausea, vomiting. Patients should eat small and frequent meals, at least 5 to 6 meals a day, to ensure that the total daily intake is sufficient. What should chemotherapy patients eat? First of all, they should make recipes according to their favorite foods and tastes, and change them frequently such as meat, fish, shrimp, crab, chicken in rotation, etc., and if possible, they can eat some turtles, turtle, deep-sea fish. Secondly, in order to stimulate the increase of appetite, you can use hawthorn, candy, lemon, onion, radish and other foods that can stimulate the appetite, and change the cooking method. Encourage patients to share their dietary experience with each other, and let those who have dietary experience to talk about their dietary experience during chemotherapy, which can increase patients’ confidence in eating. Eating should be chewed and swallowed slowly, and at least half an hour’s rest should be taken after meals, so as not to slow down the digestive function and increase the discomfort after activities. How do patients eat during chemotherapy? Most of the chemotherapeutic drugs may cause nausea, vomiting and other symptoms, and patients should not eat 2 hours before chemotherapy to avoid aggravating the vomiting. Such patients can eat a light diet and drink plenty of water, but do not consume a large amount of beverages at one time. You can eat rice, soup, porridge, etc., with appropriate flavorings during the intervals. Chemotherapeutic drugs such as fluorouracil can cause diarrhea, patients are advised to consume a low residue diet to reduce the gastrointestinal burden, such as light rice soup, yogurt, skimmed milk, fresh fruit juices, lactobacillus-containing materials, with fluids and semi-fluids, and to reduce the intake of vegetables and other coarse fiber foods. Encourage drinking more water, the daily water intake of more than 1500ml, in order to replenish water and facilitate the excretion of toxins. Maintaining good oral hygiene is essential for chemotherapy patients to ensure their diet. Clean the mouth before and after meals, before going to bed and in the morning, and when there are ulcers, you can change to use a children’s toothbrush with a smaller model and soft bristles to clean the mouth, so as to minimize the damage to the mucous membrane due to friction. Mucosal ulceration, infection, should be based on different situations using the appropriate mouthwash, such as saline, hydrogen peroxide and other gargles. At this time, avoid eating spicy, too cold or too hot and other stimulating food, should be given to the light warm semi-fluid soft food is appropriate. In short, the diet of chemotherapy patients is not set in stone, according to the individualization of reasonable adjustment, scientific diet. As a clinical staff, we should strengthen the dietary care for chemotherapy patients, and strive to improve the nutritional status of the patient’s body, so that he or she can better accept chemotherapy, promote recovery and improve the quality of life.