Esophageal cancer in advanced stage will not be cured by itself. Esophageal cancer belongs to malignant tumors of digestive system, and the treatment methods include surgery, radiotherapy, targeted drugs and immunotherapy. No matter which stage it is in, it cannot be cured by itself, and it needs to actively cooperate with the treatment in order to be cured. In the advanced stage of esophageal cancer, active treatment is needed to control the condition and shrink the tumor through palliative surgical resection, radiotherapy, chemotherapy and other comprehensive treatments, which can help to improve the patient’s quality of life and prolong his/her life cycle, and if there is obvious pain and emaciation, it is also necessary to use morphine and nutrient solution for pain relief and nutritional support treatment. Cancer has no possibility of self-healing, so it is recommended that patients actively cooperate with doctors in order to improve their symptoms, enhance the quality of life and prolong the survival period.