Brittle bones may be related to the following diseases: 1, osteoporosis may exist. This situation is most common in the elderly with osteoporosis, sometimes even a slight action, may cause related pathologic fracture, sneezing may cause rib fracture, and shoulder load, may cause thoracolumbar vertebrae compression fracture. 2, there may be osteogenesis imperfecta this kind of disease. Osteogenesis imperfecta is a kind of congenital hereditary disease, the main lesion is to cause the collagen in the bone to reduce, and then make the bone brittleness increase, even if the patient suffers a very slight external force, it is also easy to lead to fracture, but the patient after puberty, the number of fracture will gradually reduce. 3, may be due to the long-term bed-ridden caused by the wasting of the lesion. If the patient is bedridden for a long time, it is possible that the lower limbs do not get enough external stimulation, which in turn produces an increase in bone destruction and a decrease in bone formation, and when the patient suddenly goes down to the ground, it is possible that due to excessive weight-bearing, which leads to pathologic fractures of the lower limbs.