Cholinesterase activity can be calculated by fasting venous blood sampling, it is recommended to go to a regular hospital for examination. Cholinesterase is a class of glycoproteins, produced by the liver, involved in the normal function of the nervous system, present in the body in the form of a variety of isoenzymes, generally divided into true cholinesterase and pseudo cholinesterase. Cholinesterase activity is used to monitor patients for organophosphorus exposure or poisoning, to monitor cholinesterase levels in pesticide users or production workers, to identify hereditary pseudocholinesterase deficiency, and to help clinicians determine the cause of prolonged apnea after anesthesia. Decreased cholinesterase activity is common in organophosphorus poisoning, hereditary pseudocholinesterase deficiency, and liver injury; increased cholinesterase activity is common in obesity, hyperthyroidism, fatty liver, and diabetes. It is recommended to consult a doctor in time to make a clear diagnosis under the guidance of a professional physician.