Glucocorticoids have powerful anti-inflammatory, anti-rheumatic and immunosuppressive effects, and indications generally include inflammation, thrombocytopenia, sepsis and meningitis caused by various diseases. Common adverse reactions include infections, peptic ulcers, Cushing’s syndrome and so on. The use of the indications need to be strictly grasp, do not advocate long-term use. 1. Inflammation caused by various diseases: glucocorticoids can inhibit capillary dilatation, reduce exudation and edema, and can play a powerful anti-inflammatory role. It can relieve various causes of inflammation such as chronic obstructive pulmonary disease with acute exacerbation and bronchial asthma, etc. It can also rapidly improve the gouty arthritis joint pain and redness, swelling, heat and other discomforts. 2. Thrombocytopenia: Glucocorticosteroids can stimulate the bone marrow hematopoietic system to increase the number of red blood cells, hemoglobin and platelets, thus increasing the number of platelets, which is the first choice of drugs for patients with idiopathic thrombocytopenic purpura. 3. Sepsis, meningitis: glucocorticoids can inhibit the thermoregulatory center and reduce the release of endothermic sources. It can play a good antipyretic effect on high fever caused by sepsis and meningitis. In addition, glucocorticosteroids are also suitable for use in the resuscitation of all kinds of severe shock, such as toxic shock and anaphylactic shock. The common adverse reactions of glucocorticoids are infection, peptic ulcer, Cushing-like syndrome, etc.. It is contraindicated in patients who are allergic to the drug, severe hypertension, osteoporosis and so on. Pay attention to the monitoring of infection during the use of the drug, and gradually reduce the dosage before stopping the drug after long-term use. Patients are advised to seek timely medical attention and use glucocorticosteroids as prescribed by the doctor.