Causes of generalized itch include allergy, eczema, diabetes, pruritus, etc. Treatment includes medication. 1. Allergy: If the itch is caused by contact with allergic substances, it is necessary to avoid re-exposure to allergenic substances, and give antihistamines such as loratadine to stop the itch. 2. Eczema: For itching caused by eczema, anti-inflammatory treatment with glucocorticoid drugs such as halometasone cream and fluticasone propionate can be given. 3. Diabetes mellitus: If the itching is caused by diabetes mellitus skin lesions, metformin and other drugs can be given to lower sugar treatment. 4. Pruritus: For pruritus triggered by mental factors, antidepressant drugs such as paroxetine can be given. Finally, the phenomenon of generalized itching, please consult a doctor in time, the above drugs need to follow the doctor’s instructions.