In modern society, traffic accidents, production safety accidents and craniosurgery are frequent, and cranial defects inevitably occur from time to time. The skull is a very important protective organ for the human body and should be repaired in time once the defect occurs. Cranial repair is of course a traditional and ancient surgical procedure that was practiced by our ancestors thousands of years ago. After thousands of years of development and accumulation, cranial repair is a very routine and widely performed procedure in modern medicine in neurosurgery. However, the technical level of physicians varies from one place to another, and the hardware facilities are equipped differently, and the repair materials used are not the same and their performance varies, which leads to such and such problems after cranial repair in a considerable number of patients. In clinical practice, there are often patients with postoperative rejection, infection, material exposure, cutting pain, intolerance to hot and cold environment, and so on. Such cranial repair surgery is not ideal. A new PEEK material is currently used clinically as the implant material for cranial bone repair, which has the advantages of 3D printing, high temperature resistance, and similarity to autologous cranial bone. We use advanced polyetheretherketone PEEK material to perform cranial bone repair for patients, and through continuous technical improvement and optimization of material design, the repair effect is continuously improved. We have achieved good clinical results and received recognition and praise from patients.