Patients who wake up in the morning with hand swelling may generally have the following common causes A. Patients with cervical spondylosis can cause numbness and swelling of the hands of the upper limbs if the local nerve is continuously compressed. Improper posture during sleep at night can cause nerve compression at the cervical spine, aggravating the symptoms of hand swelling more pronounced after the patient wakes up in the morning. Second, patients with rheumatoid arthritis and osteoarthritis most often show stiffness, numbness, and swelling of the fingers after waking up in the morning. Generally, the symptoms of swollen and stiff fingers can be gradually relieved after appropriate activities. In this case, it is recommended that patients go to the hospital to improve the rheumatoid factor test, which can clarify the condition. Third, patients with renal insufficiency can be accompanied by swelling of the hands because of the accumulation of water in the body. Patients can actively improve the function and enhance diuresis to promote water excretion in the body, thus reducing the symptoms of hand swelling.