High-grade plasmacytoid ovarian cancer stage 3b is generally treatable, and patients are advised to go to the hospital as early as possible for surgical treatment, drug treatment, radiotherapy and chemotherapy. High-grade plasmacytoid ovarian cancer belongs to epithelial ovarian cancer with poor differentiation and high malignancy, while stage 3b is usually an advanced stage of cancer. High-grade plasmacytoid ovarian cancer stage 3b is usually more difficult to treat, and active treatment can help patients relieve uncomfortable symptoms, improve quality of life and prolong their life cycle. Generally, the treatment for high-grade plasmacytoid ovarian cancer is mainly based on surgery, supplemented by chemotherapy, radiotherapy, immunotherapy and so on. Tumor cell reduction surgery can be carried out according to the patient’s condition, and radiotherapy and chemotherapy can be used as auxiliary treatment before and after surgery. It is suggested that patients should go to the hospital in time and actively cooperate with doctors for treatment.