There are normal conditions and pathological conditions in which the stomach will gurgle. 1. Normal situation: when the patient appears to be hungry or drink a lot of water, there will also be stomach grumbling, which is a normal physiological phenomenon. 2. Pathological situation: when the patient has acute gastroenteritis, the intestinal wall edema, a large number of inflammatory cells infiltration, can also lead to gastrointestinal dysfunction, excessive peristalsis of the intestinal wall, the stomach grumbles and rumbles, causing diarrhea. When the patient has irritable bowel syndrome, due to excessive emotional fluctuations, there will also be stomach gurgling. When the patient’s stomach rumbles, it is necessary to combine with other manifestations, such as abdominal pain, diarrhea, nausea, vomiting, etc., to comprehensively assess whether it is a normal situation, and if necessary, improve the gastroscopy and enteroscopy, to clarify the cause of the disease, and then carry out the appropriate treatment.