There are two ways to deal with chemotaxis in the examination result, one is transient infection of pathogenic bacteria can be followed up and observed, and the other is persistent infection of pathogenic bacteria need to be reviewed after treatment. 1. Follow-up observation: columnar epithelial hyperplasia usually occurs due to external stimuli, when the external stimuli disappear (such as viral or bacterial erosion), hyperplasia cells will be restored, generally do not need special treatment, and can be examined regularly. 2. Review after treatment: If the pathogen (virus or bacteria) persists, it can lead to the persistence of pyogenic cells and the appearance of atypical pyogenic cells, at this time, it is necessary to give appropriate drug interventions (anti-viral therapy, such as interferon or anti-inflammatory therapy, such as cefixime, etc.), and review the treatment in 3-6 months, and based on the results of the review, then make a decision on the follow-up treatment. Chemotaxis is a manifestation of an adaptive response and is usually reversible. If they persist they may underlie the development of certain cancers such as bronchial squamous cell carcinoma or cervical cancer. In conclusion, the presence of pyogenic cells in a smear test is not necessarily precancerous, but follow-up or treatment as prescribed by the physician is recommended.