Redness, swelling, pain, etc. at the injection site after rabies vaccination, and systemic side effects such as fever and weakness may occur, but the chances of side effects are extremely low and most of them are mild. Generally patients may experience side effects such as redness, swelling, pain and itching at the injection site within 24 hours after rabies vaccination, and systemic reactions may include mild fever, vomiting, abdominal pain, weakness, headache, dizziness, arthralgia and muscular pain, which can usually be relieved on their own without any special circumstances. Rabies vaccine is a biological agent used for pre-exposure or post-exposure prevention of rabies. After rabies vaccination, anti-rabies virus antibodies can appear in the blood, and these antibodies can prevent the virus from spreading directly between cells and reduce the amount of virus proliferation, and at the same time, it can also remove free rabies virus and prevent the virus from reproducing and spreading, so as to achieve the effect of preventing rabies. It is recommended that patients should take rabies vaccine under the guidance of a doctor and inform the doctor in case of side effects of the drug.