Ankle swelling is most common in ankle sprains, and the fastest way to reduce swelling includes physical therapy and medication. 1. Physical therapy: patients with acute sprains, first of all, you need to carry out the braking of the affected limb, ice, elevate the affected limb and other treatments, if necessary, you can choose the elastic bandage for compression bandage; 72 hours after the relief period can be changed to a towel hot compresses, and at the same time, you can choose the local massage, magnetic therapy and other ways to accelerate the circulation around the joints to promote the metabolite discharge. 2. Drug therapy: sprain pain symptoms are more obvious patients can take oral ibuprofen, indomethacin and other drugs to relieve pain; can also be taken orally diosmin tablets, horse chestnut seed extract and other drugs to accelerate blood circulation in the lower limbs; can be static drip mannitol, dexamethasone and other drugs to quickly reduce swelling. All of the above medications should be used under the guidance of a doctor, avoid self-medication. If the patient’s symptoms are serious, or the symptoms continue without improvement, should go to the hospital in time for treatment.