If the patient wakes up and finds that the ankle joint is painful and unable to stand, it may be due to the ankle sprain or gouty arthritis in the ankle joint the day before. At this time, the patient can be immobilized, cold compresses, topical medications and other treatments, and then go to the orthopedic department as soon as possible to receive the next step of treatment. Specific treatment measures are as follows: 1. Fixation: At this time, patients need to temporarily use elastic bandage or ordinary bandage to fix the affected area. After that, patients should not continue to use the affected side of the foot to bear weight on the ground, and do not rub it. 2. Cold compress: It is recommended that the patient can put ice or ice-cream, wrapped in a towel, placed on the affected area of the cold compress for 10 to 20 minutes. 3. Topical medication: Patients can first apply some medication that can activate blood circulation and remove blood stasis on the affected area. For example, the common ones are blood circulation pain relief cream, Yunnan Baiyao cream and so on. 4. Further treatment: patients should go to the orthopedic department as soon as possible. At this time, if it is confirmed that there is only common ankle sprain and contusion, the patient can continue to take the above treatment. If the patient is found to have gouty arthritis, the patient should be given some anti-inflammatory and anti-gout drugs, such as diclofenac sodium and colchicine. The above drugs should be taken according to the doctor’s prescription.