Gastric cancer pT4N3M0 is stage IIIC in clinical staging, which is relatively serious, but can obtain certain clinical cure rate after treatment, so patients don’t need to be overly panicked. Gastric cancer is a common malignant tumor of digestive system, which is mostly induced by bad dietary habits, Helicobacter pylori infection and other factors. Gastric cancer pT4N3M0 is the result of pathological examination, which belongs to stage IIIC, representing that the cancer cells have infiltrated into the plasma membrane layer of the stomach to the outside of the stomach wall, and have not spread or have spread to the nearby organs or tissues; more than 7 lymph nodes metastasis have occurred locally; and there is no distant metastasis. This period belongs to the middle late stage, and is relatively serious due to the deep invasion of the tumor and more lymph node metastasis. Surgery, radiotherapy and other treatments can be performed according to the condition. After active treatment, a five-year survival rate of about 30% can be achieved.