Orchitis can be caused by bacterial infection or viral infection. Those with bacterial infection need to rub antibiotic ointment; those with viral infection need to rub antiviral ointment, and need to use the medication after clear diagnosis, and should not abuse the medication on their own. Orchitis is an inflammatory disease of the testicles caused by bacterial or viral infection. The main manifestation is redness and swelling of the scrotum on the affected side, obvious pressure and pain, which may be accompanied by nausea, vomiting, fever, chills and other systemic symptoms. It is mostly caused by purulent bacteria in the body through bloodstream infection, lymphatic infection or direct spread to the testicles. In addition, it can also be caused by the mumps virus entering the testicles through the bloodstream. 1. In testicular inflammation caused by bacterial infection, the use of antibiotics is ideally based on culture results and drug sensitivity tests, not solely on microscopic examination or Gram stain results. Broad-spectrum antibiotics may be used empirically until the pathogen is clearly identified. Topical medications for the treatment of orchitis include erythromycin ointment, clotrimazole ointment, and the traditional Chinese medicine Jinhuang Ruyi San (金黄如意散) mixed with vinegar and applied to the scrotum. 2. There is no specific antiviral drug treatment for mumps virus-induced orchitis. However, α-2b interferon is effective in preventing testicular atrophy in addition to acute mumps and viral orchitis. The above drugs need to be used under medical supervision for better treatment of the disease.