Found that the patient is injecting penicillin allergy, 1, must immediately stop the injection of penicillin, and then replaced with saline drip. 2, should be given to the patient lying down mainly, given oxygen, cardiac monitoring, close observation of vital signs. 3, immediately apply anti-allergic drugs, such as intramuscular injection of phenylephrine, but also can be applied to the intravenous injection of dexamethasone, dexamethasone has the effect of anti-inflammatory, antiallergic, anti-shock. If the patient’s heart rate increases and blood pressure decreases, there is a possibility of anaphylactic shock, in which case the patient can be treated with epinephrine, which can usually be given intramuscularly as epinephrine 0.5 mg, and also rapid rehydration of fluids to correct the symptoms of shock. Depending on the response to treatment, a decision is made as to whether or not to administer an additional epinephrine injection.